Development of Sympathetic Nervous System in Stroke-prone SHR (SHRSP)
نویسندگان
چکیده
منابع مشابه
Genetic subgrouping of stroke-prone SHR and stroke-resistant SHR.
From these results, we can conclude that the developmental pattern of hypertension in the young age is genetically determined and closely related to the incidence of hemorrhage or infarction. These newly selected substrains of SHRSP with higher incidences of cerebral infarction (SP-2) or hemorrhage (SP-1) are regarded as the better models for studying the pathogenesis, treatment, and prevention...
متن کاملPlatelet survival studies in stroke-prone spontaneously hypertensive rats (SHRSP).
Platelet survival was studied by using 51Cr-labeled platelets in stroke-prone spontaneously hypertensive rats (SHRSP), stroke-resistant SHR (SHRSR) and normotensive control rats of the Wistar-Kyoto (WK) strain. Relatively young animals of the same age prior to the development of cerebrovascular lesions (cerebral infarction and/or hemorrhage) were used. Platelet half-life time in SHRSP was sligh...
متن کاملStudies on the antioxidative potential of tissues and blood in spontaneously hypertensive rats (SHR), stroke-prone-SHR (SHRSP) and normotensive Wistar Kyoto rat (WKR).
Following the previous examinations on lipid peroxide (LPO) and related enzyme activities in male SHR and SHRSP (Jap Heart J 18: 608, 1977), further studies were conducted with both male and female SHR, SHRSP, and WKR. LPO in tissue homogenate or serum pretreated with sodium dodecyl sulfate (SDS) was measured by colorimetric (OD532nm) and/or fluorometric (Ex515nm, Em555nm) method according to M...
متن کاملPermeability of intracranial extracerebral vessels in stroke-prone SHR.
Permeability of intracranial extracerebral arteries of stroke-prone spontaneously hypertensive rats (SHRSP) was studied using labeling techniques (ferritin and horseradish peroxidase), at the cellular level. In the arterial endothelial cells, the tracer molecules were slowly but constantly transported by the plasmalemmal vesicles to the subendothelial space. This endothelial transportation of t...
متن کاملRole of prostaglandins in the development of stroke in stroke-prone spontaneously hypertensive rats (SHRSP)-preliminary report
Plama levels of 6-keto prostaglandin Fla (6-keto PGFIa) and thromboxane B2 (TXB2) derivatives of prostacyclin (PGI2) and thromboxane A2, respectively, were measured in female stroke-prone spontaneously hypertensive rat (SHRSP), stroke-resistant SHR (SHRSR) and Wister-Kyoto rats (WKY) of various ages. Gas chromatograph-mass spectrometer was used for the analysis. The 6-keto PGFIa level was decre...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 1979
ISSN: 0021-4868,1348-673X
DOI: 10.1536/ihj.20.727